St. Rose of Lima Parish was founded October 12, 1948. The parish was led by Monsignor James F. Enright, who established the school on September 12, 1951. The first Principal was Sister Kathleen Marie, an Adrian Dominican. With one class per grade, 412 students were enrolled in Kindergarten through Sixth Grade in the 12 original school rooms. Additional classrooms were constructed in September 1954, and Grades 7 through 9 were added. School enrollment reached 737 pupils. In May 1955, the first Ninth Grade class graduated from St. Rose.
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